COVID-19 vaccinated individuals may be ill…See more…

Immune response: Vaccines train the immune system to recognize SARS-CoV-2 and mount a rapid defense.
Platforms: mRNA (Pfizer, Moderna), protein-based (Novavax), and adenovirus-vectored vaccines remain widely used.
Boosters: Updated formulations target newer variants like JN.1, improving protection against circulating strains.
- Hospitalization Protection: Updated vaccines reduced hospitalizations by ~55% among adults with COVID-like illness.
- Emergency Care Visits: Effectiveness against ED/urgent care visits was ~50%, showing strong real-world impact.
- Variant Adaptation: Omicron-adapted boosters provide superior protection compared to older monovalent doses.